Endotoxin Stimulation in Patients With Lymphoma: Correlation With the Myelosuppressive Effects of Alkylating Agents

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Endotoxin stimulation in patients with lymphoma: correlation with the myelosuppressive effects of alkylating agents.

Estimates of the bone marrow granulocyte reserve were made in 97 patients with lymphoma utilizing the endotoxin Pyrexal. Normal granulocyte responses were observed in most patients who had not received prior myelosuppressive therapy. Patients with lymphosarcoma responded as well as those with Hodgkin’s Disease. All patients with Ieukopenia due to previous therapy or marrow infiltration failed t...

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